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  • idursulfase


Pronunciation: EYE dur SUL fase

Brand: Elaprase

What is the most important information I should know about idursulfase?

Multum emt

Some side effects may occur during the idursulfase infusion, or up to 24 hours afterward. Get emergency medical help if you have any of these signs of an allergic reaction: feeling like you might pass out; hives; trouble breathing; seizure (convulsions); swelling of your face, lips, tongue, or throat.

You may be more likely to have a reaction to idursulfase if you have a breathing disorder.

What is idursulfase?

Idursulfase is used to treat some of the symptoms of a genetic condition called Hunter's syndrome, also called mucopolysaccharidosis (MYOO-koe-pol-ee-SAK-a-rye-DOE-sis).

Hunter syndrome is a metabolic disorder in which the body lacks the enzyme needed to break down certain sugars and proteins. These substances can build up in the body, causing enlarged organs, abnormal bone structure, changes in facial features, breathing problems, heart problems, vision loss, and changes in mental or physical abilities.

Multum donot

Idursulfase may improve walking ability in people with this condition. However, this medication is not a cure for Hunter syndrome.

Idursulfase may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving idursulfase?

Multum donot

You should not receive this medication if you are allergic to idursulfase.

To make sure idursulfase is safe for you, tell your doctor if you have asthma or any other lung problems. You may be more likely to have a reaction to idursulfase if you have a breathing disorder.

Your name may need to be listed on a Hunter Outcome Survey while you are using this medication. The purpose of this registry is to track the progression of this disorder and the effects that idursulfase has on long-term treatment of Hunter syndrome.

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FDA pregnancy category C. It is not known whether idursulfase will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

It is not known whether idursulfase passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is idursulfase given?

Idursulfase is injected into a vein through an IV. You will most likely receive this injection in a clinic or hospital setting.

Idursulfase must be given slowly through an IV infusion, and can take up to 3 hours or longer to complete.

Your doctor may also prescribe other medications to help prevent an allergic reaction to galsulfase. Take all of your medications as directed.

Idursulfase is usually given once per week. Follow your doctor's instructions.

Your doctor will need to check your progress while you are using galsulfase.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your idursulfase injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving idursulfase?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of idursulfase?

Multum emt

Some side effects may occur during the idursulfase infusion, or up to 24 hours afterward. Get emergency medical help if you have any of these signs of an allergic reaction: feeling like you might pass out; hives; trouble breathing, seizure (convulsions); swelling of your face, lips, tongue, or throat.

It may still be possible for you to receive idursulfase even after you have had a reaction to it. There are other medications that can be given to you before your idursulfase infusion to help prevent symptoms of a reaction.

Common side effects may include:

  • vomiting, diarrhea;
  • headache;
  • fever, cough;
  • itching, mild skin rash; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect idursulfase?

Other drugs may interact with idursulfase, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your doctor or pharmacist can provide more information about idursulfase.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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