Metoclopramide

Examples

Generic Name Brand Name
metoclopramide Reglan

Metoclopramide may be given as a shot in the vein (intravenous, or IV) or in pill form.

How It Works

Metoclopramide increases the movements or contractions of the muscles in the stomach and intestines. This decreases the amount of time it takes for the stomach contents to move through the digestive tract.

Why It Is Used

Metoclopramide prevents and relieves nausea and vomiting caused by chemotherapy. It is also used to treat heartburn, loss of appetite, and a prolonged feeling of fullness after meals.

How Well It Works

Metoclopramide improves nausea and vomiting that is caused by chemotherapy or advanced cancer.

Side Effects

Metoclopramide does not cause as many side effects as many other medicines used to prevent nausea and vomiting. Side effects may include:

  • Sleepiness or confusion.
  • Twitching or muscle spasms.
  • Decreased blood pressure (hypotension).
  • Rapid or uncontrolled movements of lips and tongue.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Do not use metoclopramide if you have narrow-angle glaucoma, prostate disease, severe low blood pressure, or rapid, irregular heartbeats.

Metoclopramide can cause sleepiness and confusion, so do not operate motor vehicles or other machinery until you know how you react to this medicine.

Do not drink alcohol while you are taking metoclopramide.

Metoclopramide can interact with many other medicines. Check with your doctor before taking other medicines, such as antihistamines or cold medicines, sedatives, tranquilizers, sleeping pills, pain medicines, seizure medicines, or muscle relaxants.

Complete the new medication information form (PDF)new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Credits

By Healthwise Staff
Sarah Marshall, MD - Family Medicine
Douglas A. Stewart, MD - Medical Oncology
Last Revised August 14, 2013

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

© 1995-2014 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

First Nurse

First Nurse

Call First Nurse 24 Hours a Day for free health care advice, resources and referrals!

Ames: 515-239-6877
In Iowa: 800-524-6877 

Search health information online in our Mulimedia Health Library.

Symptom Checker

Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.

Symptom Checker

Patient Privacy | Net Learning for Employees | MGMC PACS for Physicians
Emergency Preparedness

1111 Duff Avenue Ames, IA 50010 - 515-239-2011 - yourhealth.mgmc@mgmc.com

©2014 Mary Greeley Medical Center - All rights reserved.