Thrombocytopenia, Essential

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Thrombocytopenia, Essential is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • TTP

Disorder Subdivisions

  • Idiopathic Thrombocytopenic Purpura
  • ITP
  • Werlhof's Disease
  • Purpura Hemorrhagica
  • Thrombotic Thrombocytopenic Purpura
  • Moschowitz Disease, Essential
  • Hemolytic-Uremic Syndrome
  • HUS

General Discussion

Essential thrombocytopenia is a rare blood disease characterized by reduced levels of platelets in the circulating blood. Platelets are essential to blood-clotting and, if they are in short supply, bleeding may occur that can become life-threatening. The platelets are produced in the bone marrow and may be in reduced supply because of (1) impaired or reduced platelet production in the marrow, (2) increased destruction of platelets faster than they can be replaced by the marrow, or (3) the presence of one of several genetic disorders. There are also false thrombocytopenias. Major symptoms include a tendency to bleed excessively into the skin or mucous membranes, especially during menstruation, nosebleeds and bleeding gums.

Resources

NIH/National Heart, Lung and Blood Institute
P.O. Box 30105
Bethesda, MD 20892-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov
Internet: http://www.nhlbi.nih.gov/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  3/28/2008
Copyright  1988, 1989, 1992, 1998, 2006 National Organization for Rare Disorders, Inc.

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