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  • tesamorelin
 

tesamorelin

Pronunciation: TES a moe REL in

Brand: Egrifta

What is the most important information I should know about tesamorelin?

Multum nopreg

Tesamorelin can harm an unborn baby or cause birth defects. Do not use if you are pregnant.

Multum donot

You should not use tesamorelin if you are allergic to it, or if you have a history of tumor or surgery of your pituitary gland, a history of head injury or radiation treatment,

Before using tesamorelin, tell your doctor if you have heart disease, high blood pressure, kidney disease, diabetes, epilepsy, asthma, migraines, an adrenal gland disorder, or if you have ever had cancer, any type of tumor, or open heart surgery.

Also tell your doctor about any major illness or recent trauma or medical emergency.

What is tesamorelin?

Tesamorelin is made with growth hormone-releasing factor (GRF).

Tesamorelin is used to reduce excess fat around the stomach that is caused by taking certain HIV medications. This condition is also called lipodystrophy (LYE-poe-DIS-troe-fee).

Multum donot

Tesamorelin is not a weight-loss medication and should not be used to treat obesity.

What should I discuss with my healthcare provider before using tesamorelin?

Multum donot

You should not use tesamorelin if you are allergic to it, or if you have:

  • cancer;
  • a pituitary gland disorder;
  • a history of pituitary gland tumor or surgery;
  • a history of head injury or radiation treatment; or
  • if you are pregnant.

To make sure you can safely take tesamorelin, tell your doctor if you have any of these other conditions:

  • a history of cancer or any tumor (either benign or malignant);
  • heart disease, high blood pressure;
  • kidney disease;
  • diabetes, eye problems caused by diabetes;
  • epilepsy
  • asthma;
  • migraine headaches;
  • adrenal gland disorder;
  • if you have ever had open heart surgery; or
  • if you have any major illness, or a recent trauma or medical emergency.
Multum nopreg

FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use tesamorelin if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

Multum nobrfeed

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Multum nochild

Do not give this medicine to a child without medical advice.

How tesamorelin given?

Tesamorelin is injected under the skin. You may be shown how to use injections at home. Do not self inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

This medication comes with injection instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Tesamorelin is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.

Multum donot

Prepare your dose in a syringe only when you are ready to give yourself an injection. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.

Multum emt

After mixing tesamorelin with a diluent, you must use it right away. Do not store the mixture for later use.

Tesamorelin is usually given once per day. Follow your doctor's dosing instructions very carefully.

Use a different place on your stomach each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row.

Multum donot

Never share a tesamorelin syringe with another person, even if you change the needle. Sharing syringes or needles can allow HIV or other diseases to pass from one person to another.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Do not miss any follow-up visits to your doctor.

Multum refig

Store vials of tesamorelin powder in the refrigerator, do not freeze.

Multum rt

Store the diluent at room temperature away from moisture, heat, and light.

Throw away any unused vials after the expiration date on the label has passed.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of tesamorelin.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using tesamorelin?

Do not inject this medicine into scar tissue or on skin that is bruised. Do not inject directly into your navel (belly-button).

What are the possible side effects of tesamorelin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop using tesamorelin and call your doctor at once if you have a serious side effect such as:

  • swelling in your hands, ankles, or feet;
  • pain or stiffness in your muscles or joints;
  • pain in your arms or legs;
  • wrist pain or numbness;
  • numbness or tingling in your hands or fingers;
  • pounding heartbeats or fluttering in your chest;
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);

Less serious side effects may include:

  • depressed mood, sleep problems (insomnia);
  • night sweats;
  • mild rash or itching;
  • muscle spasm;
  • nausea, vomiting, upset stomach;
  • pain, redness, itching, swelling, bruising, bleeding, or other irritation where the injection was given;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect tesamorelin?

Tell your doctor about all other medicines you use, especially:

  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • testosterone or hormone replacement therapy;
  • seizure medication;
  • steroids (prednisone and others);

This list is not complete and there are many other drugs that can interact with tesamorelin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about tesamorelin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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