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  • insulin aspart and insulin aspart protamine
 

insulin aspart and insulin aspart protamine

Pronunciation: IN su lin AS part, IN su lin AS part PRO ta meen

Brand: NovoLOG Mix 70/30, NovoLOG Mix 70/30 FlexPen, NovoLOG Mix 70/30 PenFill

What is the most important information I should know about insulin aspart and insulin aspart protamine?

Take care not to let your blood sugar get too low. Low blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency.

Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, loss of appetite, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Your blood sugar will need to be checked often, and you may need to adjust your insulin aspart and insulin aspart protamine dose.

Multum donot

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

What is insulin aspart and insulin aspart protamine?

Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart and insulin aspart protamine is a faster-acting form of insulin than regular human insulin.

Insulin aspart and insulin aspart protamine is used to treat type 1 (insulin-dependent) diabetes in adults.

Insulin aspart and insulin aspart protamine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using insulin aspart and insulin aspart protamine?

Multum donot

Do not use this medication if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).

To make sure you can safely use insulin aspart and insulin aspart protamine, tell your doctor if you have liver or kidney disease.

This medication is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.

FDA pregnancy category B. Insulin aspart and insulin aspart protamine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether insulin aspart and insulin aspart protamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use insulin aspart and insulin aspart protamine?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Insulin aspart and insulin aspart protamine is injected under the skin. You will be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

Multum donot

Insulin aspart and insulin aspart protamine must not be given with an insulin pump, or mixed with other insulins.

Multum food

After using insulin aspart and insulin aspart protamine, you should eat a meal within 15 minutes. This medication is usually given with 2 meals per day.

Just before using this medication, roll the vial (medicine bottle) 10 times between the palms of your hands, until the medicine looks white and cloudy. Then give the injection right away.

If you use the injection pen, turn it upside down so the glass ball inside it moves from one end to the other. Do this at least 10 times, until the medicine looks white and cloudy, then give the injection right away. Repeat this procedure each time you use the injection pen.

Choose a different place in your injection skin area each time you use this medication. Do not inject into the same place two times in a row.

Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Multum donot

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

Multum dizzy

Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating.

Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.

Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, loss of appetite, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.

Your doctor may want you to stop taking insulin aspart and insulin aspart protamine for a short time if you become ill, have a fever or infection, or if you have surgery or a medical emergency.

Multum donot

Ask your doctor how to adjust your insulin aspart and insulin aspart protamine dose if needed. Do not change your medication dose or schedule without your doctor's advice.

Multum refig

Storing unopened vials or injection pens: Keep in the carton and store in a refrigerator, protected from light. Throw away any insulin not used before the expiration date on the medicine label.

Multum rt

Unopened vials or injection pens may also be stored at room temperature for up to 28 days, away from heat and bright light. Throw away any insulin not used within 28 days.

Multum refig

Storing vials after your first use: You may keep "in-use" vials in the refrigerator, protected from light. Use within 28 days.

Multum rt

You may also keep in-use" vials at room temperature. Use within 28 days. Protect from light.

Multum rt

Storing injection pens after your first use: Keep the "in-use" injection pen at room temperature and use within 28 days. Do not refrigerate. Protect from light.

Do not freeze this medication, and throw away the medication if it has become frozen.

What happens if I miss a dose?

Since insulin aspart and insulin aspart protamine is used before meals, you may not be on a timed dosing schedule. Whenever you use this medication, be sure to eat a meal within 15 minutes. Do not use extra insulin aspart and insulin aspart protamine to make up a missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What should I avoid while using insulin aspart and insulin aspart protamine?

Multum noalcohol

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

What are the possible side effects of insulin aspart and insulin aspart protamine?

Multum emt

Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out.

Hypoglycemia, or low blood sugar, is the most common side effect of insulin. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • vision changes;
  • swelling in your hands or feet; or
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin aspart and insulin aspart protamine.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect insulin aspart and insulin aspart protamine?

Tell your doctor about all other medications you use, especially:

  • albuterol (Proventil, Ventolin);
  • clonidine (Catapres);
  • disopyramide (Norpace);
  • niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and otheres);
  • pramlintide (Symlin);
  • fenofibrate (Antara, Lipofen, Triglide), fenofibric acid (Trilipix), or gemfibrozil (Lopid);
  • enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others;
  • aspirin or other salicylates (including Pepto-Bismol);
  • birth control pills and other hormones;
  • diet pills or medicines to treat asthma, colds or allergies;
  • diuretics (water pills);
  • a monoamine oxidase inhibitor (MAOI);
  • phenothiazines (Phenergan and others);
  • thyroid medicine (Synthroid and others);
  • a beta-blocker (Tenormin, Normodyne, Toprol, Coreg, Inderal, and others);
  • medicines to treat psychiatric disorders (Abilify, Clozaril, Zyprexa, Compazine, Risperdal, and others);
  • steroids (prednisone and others); or
  • sulfa drugs (Bactrim, Septra, and others).

This list is not complete and there are many other medicines that can increase or decrease the effects of insulin on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about insulin aspart and insulin aspart protamine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 7.03. Revision date: 6/16/2012.

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