Health Library

  • verteporfin
 

verteporfin

Pronunciation: VER te PORE fin

Brand: Visudyne

What is the most important information I should know about verteporfin?

Multum donot

You should not receive this medication if you are allergic to verteporfin, or if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Before receiving verteporfin, tell your doctor if you have liver or gallbladder disease, or if you are receiving radiation treatment. Also tell your doctor if you are pregnant or breast-feeding.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

Multum nosun

Verteporfin will make your eyes and your skin more sensitive to light. After receiving verteporfin, you must protect your eyes and skin from natural sunlight and bright indoor light for at least 5 days.

Wear dark sunglasses and keep all parts of your skin covered with clothing. Sunscreen will not be effective in protecting you from UV rays during the 5-day period after you have received verteporfin.

What is verteporfin?

Verteporfin works by enhancing the eye's sensitivity to light. Verteporfin affects abnormal blood vessels in the eye.

Verteporfin is used together with "photodynamic" laser light therapy to treat blood vessel disorders in the eye caused by macular degeneration and other eye diseases.

Verteporfin may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before I receive verteporfin?

Multum donot

You should not receive this medication if you are allergic to verteporfin, or if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

To make sure you can safely receive verteporfin, tell your doctor if you have other medical conditions, especially:

  • liver disease;
  • gallbladder disease; or
  • if you are receiving radiation treatment.
Multum nopreg

FDA pregnancy category C. It is not known whether verteporfin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

Verteporfin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using verteporfin.

How is verteporfin given?

Verteporfin is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Verteporfin must be given slowly, and the IV infusion can take at least 10 minutes to complete.

Multum emt

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

You will receive laser light treatment to your eye(s) within 15 minutes after the start of your verteporfin infusion.

Multum nosun

After receiving verteporfin, you must protect your eyes from natural sunlight and bright indoor light for at least 5 days.. For best protection, wear dark sunglasses whenever you are outdoors or while indoors under bright lighting.

You should not stay in the dark while you are indoors, as this can actually cause the drug to stay active in your body longer. It is best to spend your time in ambient indoor light such as indirect sunlight through a window, or low-wattage incandescent lighting. Avoid areas where you will be exposed to halogen or fluorescent light.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

What happens if I miss a dose?

Since verteporfin is given by a healthcare professional only in preparation for laser light treatment, you will not be on a frequent dosing schedule.

Multum donot

Your doctor should check your condition every 3 months to determine if you need repeat treatment.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severely decreased vision.

What should I avoid after I receive verteporfin?

Multum nosun

Verteporfin will make your eyes and your skin more sensitive to light. Natural sunlight and bright indoor light can expose you to harmful UV rays, which may cause severe sunburn or damage to your vision.

Avoid exposure to sunlight, tanning beds, bright halogen lights, or other bright lighting for at least 5 days after you are treated with verteporfin.

To avoid exposing your skin to sunlight, keep all parts of your skin covered with clothing. Sunscreen will not be effective in protecting you from UV rays during the 5-day period after you have received verteporfin.

Multum dizzy

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What are the possible side effects of verteporfin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; sweating; dizziness; swelling of your face, lips, tongue, or throat.

Multum donot

Tell your caregivers at once if you have a serious side effect such as:

  • severe decrease in vision;
  • sudden and severe pain;
  • severe redness or other discoloration of your eyes;
  • eye pain or seeing halos around lights;
  • feeling like you might pass out;
  • chest pain; or
  • flushing (warmth, redness, or tingly feeling).

Less serious side effects may include:

  • slight changes in your vision, seeing flashes of light;
  • dry eyes;
  • redness, swelling, or itching of your eyelids;
  • headache;
  • feeling weak or tired;
  • mild itching or skin rash;
  • constipation, nausea;
  • joint pain, muscle weakness;
  • fever, chills, body aches, sore throat, flu symptoms; or
  • pain, swelling, bleeding, or itching where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect verteporfin?

Tell your doctor about all other medicines you use, especially:

  • dimethyl sulfoxide (Rimso-50);
  • griseofulvin (Fulvicin, Grisactin);
  • polymyxin B (Polytrim, AK-Poly-Bac, Ocumycin, Polysporin Ophthalmic, Polytracin Ophthalmic);
  • diabetes medications you take by mouth;
  • a diuretic (water pill);
  • sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);
  • medication used to prevent blood clots, such as abciximab (ReoPro), argatroban (Acova), bivalirudin (Angiomax), clopidogrel (Plavix), dabigatran (Pradaxa), dalteparin (Fragmin), dipyridamole (Persantine, Aggrenox), enoxaparin (Lovenox), eptifibatide (Integrilin), fondaparinux (Arixtra), lepirudin (Refludan), prasugrel (Effient), rivaroxaban (Xarelto), ticlopidine (Ticlid), tinzaparin (Innohep), tirofiban (Aggrastat), or warfarin (Coumadin, Jantoven);
  • a phenothiazine such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Mellaril), or trifluoperazine (Stelazine);
  • an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), and others;
  • a tetracycline antibiotic such as doxycycline (Doryx, Oracea, Periostat, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap); or
  • heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan, Tarka), and others.

This list is not complete and other drugs may interact with verteporfin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about verteporfin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 2.01. Revision date: 9/13/2012.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

First Nurse

First Nurse

Call First Nurse 24 Hours a Day for free health care advice, resources and referrals!

Ames: 515-239-6877
In Iowa: 800-524-6877 

Search health information online in our Mulimedia Health Library.

High Quality Care

Guardian of Excellence

Mary Greeley consistently delivers high quality patient care.

  • 2013 Guardian of Excellence Award for Clinical Quality
  • Grade 'A' Patient Safety from the Leapfrog Group
  • 2013 Top Performer on Key Quality Measures ranking from The Joint Commission
  • Highest percentage bonus of any Iowa hospital in Medicare's quality incentive program

Mary Greeley on Facebook

Like us on Facebook

Patient Privacy | Net Learning for Employees | MGMC PACS for Physicians
Emergency Preparedness

1111 Duff Avenue Ames, IA 50010 - 515-239-2011 - yourhealth.mgmc@mgmc.com

©2014 Mary Greeley Medical Center - All rights reserved.