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  • dextromethorphan, guaifenesin, and phenylephrine
 

dextromethorphan, guaifenesin, and phenylephrine

Pronunciation: dex troe meth OR fan, gwye FEN e sin, fen il EFF rin

Brand: Broncotron-D, Dacex-DM, Dacex-PE, Deconex DM, Deconex DMX, Despec DM Syrup, DuraMAX, Duraphen DM, Duraphen Forte, Endacon, Guaphen Forte, Maxiphen-G DM, Mucinex Children's Multi-Symptom Cold, Mucinex Fast-Max Severe Congestion & Cough, Phlemex Forte, Pres Gen Pediatric, Q-Tussin CF, Robafen CF, Robitussin Children's Cough & Cold CF, Robitussin Cough & Cold CF, Robitussin Cough & Cold CF Max, Robitussin Cough & Cold CF To Go, Robitussin Maximum Strength Multi-Symptom Cold, Robitussin Multi-Symptom Cold, Robitussin Pediatric Cough & Cold CF, Supress-DX, Tusicof, Tussi-Pres, Tussi-Pres Pediatric, Tussin CF, Z-tuss DM, Zotex-EX

What is the most important information I should know about dextromethorphan, guaifenesin, and phenylephrine?

Multum emt

Do not use this medicine if you have untreated or uncontrolled diseases such as high blood pressure or coronary artery disease.

Multum donot

Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

What is dextromethorphan, guaifenesin, and phenylephrine?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of dextromethorphan, guaifenesin, and phenylephrine is used to treat cough, stuffy nose, sinus congestion and chest congestion caused by allergies, the common cold, or the flu.

Multum smoking

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan, guaifenesin, and phenylephrine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking dextromethorphan, guaifenesin, and phenylephrine?

Multum emt

Do not use this medicine if you have untreated or uncontrolled diseases such as high blood pressure or coronary artery disease.

Multum donot

Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • diabetes;
  • glaucoma;
  • epilepsy or other seizure disorder;
  • enlarged prostate or urination problems;
  • pheochromocytoma (an adrenal gland tumor); or
  • cough with mucus, or cough caused by emphysema or chronic bronchitis.
Multum nopreg

FDA pregnancy category C. It is not known whether dextromethorphan, guaifenesin, and phenylephrine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Multum nobrfeed

Dextromethorphan, guaifenesin, and phenylephrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take dextromethorphan, guaifenesin, and phenylephrine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Do not take for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

Multum nochild

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Multum nocrush

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Multum emt

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Multum rt

Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking dextromethorphan, guaifenesin, and phenylephrine?

Multum dizzy

This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Multum noalcohol

Drinking alcohol can increase certain side effects of dextromethorphan, guaifenesin, and phenylephrine.

Multum donot

Ask a doctor or pharmacist before using any other cold, cough, or allergy medicine. Dextromethorphan, guaifenesin, and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains a decongestant, expectorant, or cough suppressant.

What are the possible side effects of dextromethorphan, guaifenesin, and phenylephrine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • fast or uneven heart rate;
  • severe dizziness or anxiety, feeling like you might pass out;
  • severe headache;
  • mood changes;
  • fever; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

Less serious side effects may include:

  • diarrhea;
  • dizziness, drowsiness;
  • sleep problems (insomnia); or
  • feeling nervous, restless, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect dextromethorphan, guaifenesin, and phenylephrine?

Ask a doctor or pharmacist if it is safe for you to take this medicine if you are also using an antidepressant, such as:

  • amitriptyline (Elavil, Vanatrip, Limbitrol);
  • citalopram (Celexa);
  • doxepin (Sinequan, Silenor);
  • duloxetine (Cymbalta);
  • escitalopram (Lexapro);
  • fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra, Symbyax);
  • fluvoxamine (Luvox);
  • nortriptyline (Pamelor);
  • paroxetine (Paxil, Pexeva);
  • sertraline (Zoloft);
  • trazodone (Desyrel, Oleptro);
  • venlafaxine (Effexor); or
  • vilazodone (Viibryd).

This list is not complete and other drugs may interact with dextromethorphan, guaifenesin, and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about dextromethorphan, guaifenesin, and phenylephrine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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