Health Library

  • hydrochlorothiazide and lisinopril
 

hydrochlorothiazide and lisinopril

Pronunciation: HYE droe KLOR oh THYE a zide and lye SIN oh pril

Brand: Prinzide, Zestoretic

HCT-Lisinopril 12.5 mg-20 mg-RAN

round, yellow, imprinted with RX 537

Image of HCT-Lisinopril 12.5 mg-20 mg-RAN
slide 1 of 28
    

Lisinopril-HCTZ 10-12.5 mg-APO

oval, pink, imprinted with 10 12.5, APO

Image of Lisinopril-HCTZ 10-12.5 mg-APO
slide 2 of 28
    

Lisinopril-HCTZ 20-25 mg-EON

round, pink, imprinted with E 173

Image of Lisinopril-HCTZ 20-25 mg-EON
slide 3 of 28
    

Prinzide 20-25 mg

round, yellow, imprinted with PRINZIDE, MSD 142

Image of Prinzide 20-25 mg
slide 4 of 28
    

Zestoretic 10-12.5

round, peach, imprinted with ZESTORETIC, 141

Image of Zestoretic 10-12.5
slide 5 of 28
    

HCT-Lisinopril 25 mg-20 mg-RAN

round, peach, imprinted with RX 538

Image of HCT-Lisinopril 25 mg-20 mg-RAN
slide 6 of 28
    

HCTZ-Lisinopril 12.5 mg-10 mg-IVA

round, blue, imprinted with 10/12.5, Logo 5033

Image of HCTZ-Lisinopril 12.5 mg-10 mg-IVA
slide 7 of 28
    

HCTZ-Lisinopril 25 mg-20 mg-TEV

round, pink, imprinted with 93, 1037

Image of HCTZ-Lisinopril 25 mg-20 mg-TEV
slide 8 of 28
    

Lisinopril-HCTZ 10-12.5 mg-EON

round, pink, imprinted with E 71

Image of Lisinopril-HCTZ 10-12.5 mg-EON
slide 9 of 28
    

Lisinopril-HCTZ 10-12.5 mg-MYL

round, white, imprinted with M, LH1

Image of Lisinopril-HCTZ 10-12.5 mg-MYL
slide 10 of 28
    

Lisinopril-HCTZ 20-12.5 mg-APO

oval, white, imprinted with 20 12.5, APO

Image of Lisinopril-HCTZ 20-12.5 mg-APO
slide 11 of 28
    

Lisinopril-HCTZ 20-25 mg-WAT

round, pink, imprinted with WATSON 862

Image of Lisinopril-HCTZ 20-25 mg-WAT
slide 12 of 28
    

Prinizide 12.5 mg-10 mg

hexagonal, white, imprinted with PRINZIDE, MSD 145

Image of Prinizide 12.5 mg-10 mg
slide 13 of 28
    

Zestoretic 20-12.5

round, white, imprinted with ZESTORETIC, 142

Image of Zestoretic 20-12.5
slide 14 of 28
    

HCT-Lisinopril 12.5 mg-10 mg-RAN

round, blue, imprinted with RX 536

Image of HCT-Lisinopril 12.5 mg-10 mg-RAN
slide 15 of 28
    

HCT-Lisinopril 25 mg-20 mg-GG

round, peach, imprinted with GP 123

Image of HCT-Lisinopril 25 mg-20 mg-GG
slide 16 of 28
    

HCTZ-Lisinopril 12.5 mg-20 mg-TEV

round, white, imprinted with 93, 1036

Image of HCTZ-Lisinopril 12.5 mg-20 mg-TEV
slide 17 of 28
    

Lisinopril-HCTZ 10-12.5 mg-WAT

round, pink, imprinted with WATSON 860

Image of Lisinopril-HCTZ 10-12.5 mg-WAT
slide 18 of 28
    

Lisinopril-HCTZ 20-12.5 mg-EON

round, white, imprinted with E 152

Image of Lisinopril-HCTZ 20-12.5 mg-EON
slide 19 of 28
    

Lisinopril-HCTZ 20-12.5 mg-MYL

round, yellow, imprinted with M, LH2

Image of Lisinopril-HCTZ 20-12.5 mg-MYL
slide 20 of 28
    

Lisinopril-HCTZ 20-12.5 mg-WAT

round, blue, imprinted with WATSON 861

Image of Lisinopril-HCTZ 20-12.5 mg-WAT
slide 21 of 28
    

Prinizide 12.5 mg-20 mg

round, yellow, imprinted with MSD 140, PRINZIDE

Image of Prinizide 12.5 mg-20 mg
slide 22 of 28
    

HCTZ-Lisinopril 12.5 mg-10 mg-TEV

round, peach, imprinted with 93, 1035

Image of HCTZ-Lisinopril 12.5 mg-10 mg-TEV
slide 23 of 28
    

HCTZ-Lisinopril 12.5 mg-20 mg-IVA

round, yellow, imprinted with 20/12.5, Logo 5034

Image of HCTZ-Lisinopril 12.5 mg-20 mg-IVA
slide 24 of 28
    

HCTZ-Lisinopril 25 mg-20 mg-IVA

round, pink, imprinted with 20/25, Logo 5032

Image of HCTZ-Lisinopril 25 mg-20 mg-IVA
slide 25 of 28
    

Lisinopril-HCTZ 20-25 mg-APO

oval, pink, imprinted with 20 25, APO

Image of Lisinopril-HCTZ 20-25 mg-APO
slide 26 of 28
    

Lisinopril-HCTZ 20-25 mg-MYL

round, green, imprinted with M, LH3

Image of Lisinopril-HCTZ 20-25 mg-MYL
slide 27 of 28
    

Zestoretic 20-25

round, peach, imprinted with ZESTORETIC, 145

Image of Zestoretic 20-25
slide 28 of 28
    

What is the most important information I should know about hydrochlorothiazide and lisinopril?

Multum nopreg

Do not use if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant.

Multum donot

You should not use this medication if you have hereditary angioedema, if you are unable to urinate, if you are allergic to sulfa drugs, or if you have ever had a severe allergic reaction to any ACE inhibitor.

If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

What is hydrochlorothiazide and lisinopril?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Lisinopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Lisinopril lowers blood pressure and also relieves symptoms of fluid retention.

Hydrochlorothiazide and lisinopril is a combination medicine used to treat hypertension (high blood pressure).

Hydrochlorothiazide and lisinopril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and lisinopril?

Multum donot

You should not use this medication if you are allergic to hydrochlorothiazide or lisinopril, or if you have:

  • hereditary angioedema;
  • if you are unable to urinate;
  • an allergy to sulfa drugs; or
  • if you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril, trandolapril).

If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

You may also need to avoid taking hydrochlorothiazide and lisinopril with aliskiren if you have kidney disease.

To make sure hydrochlorothiazide and lisinopril is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • glaucoma;
  • heart disease or congestive heart failure;
  • asthma or allergies;
  • gout;
  • lupus;
  • diabetes; or
  • an allergy to sulfa drugs or penicillin.
Multum nopreg

FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Hydrochlorothiazide and lisinopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.

Multum nobrfeed

Hydrochlorothiazide and lisinopril can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and lisinopril?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Multum water

Take each dose with a full glass of water.

Multum calldoc

You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.

While using hydrochlorothiazide and lisinopril, you may need frequent blood tests at your doctor's office. Your blood pressure will need to be checked often.

If you need surgery or medical tests, tell the doctor ahead of time that you are taking medication that contains hydrochlorothiazide. You may need to stop using the medicine for a short time.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Multum rt

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking hydrochlorothiazide and lisinopril?

Multum noalcohol

Drinking alcohol can increase certain side effects of hydrochlorothiazide and lisinopril.

Multum dizzy

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and lisinopril, unless your doctor has told you to.

What are the possible side effects of hydrochlorothiazide and lisinopril?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • eye pain, vision problems;
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • dry mouth, nausea, vomiting;
  • feeling weak, drowsy, or restless;
  • a red, blistering, peeling skin rash;
  • psoriasis (raised, silvery flaking of the skin);
  • jaundice (yellowing of the skin or eyes);
  • little or no urinating;
  • swelling, weight gain, feeling short of breath; or
  • fever, chills, body aches, flu symptoms.

Common side effects may include:

  • cough;
  • headache, tired feeling, depressed mood;
  • diarrhea, constipation, upset stomach; or
  • mild skin rash, increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and lisinopril?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with hydrochlorothiazide and lisinopril, especially:

  • barbiturates--phenobarbital and others;
  • cholestyramine or colestipol;
  • gold injections to treat arthritis;
  • insulin or diabetes medicine taken by mouth;
  • lithium;
  • narcotic pain medicine;
  • NSAIDs (non-steroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
  • other diuretics (water pills) or blood pressure medications; or
  • steroids (prednisone and others).

This list is not complete. Other drugs may interact with hydrochlorothiazide and lisinopril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and lisinopril.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 12.01. Revision date: 5/21/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

First Nurse

First Nurse

Call First Nurse 24 Hours a Day for free health care advice, resources and referrals!

Ames: 515-239-6877
In Iowa: 800-524-6877 

Search health information online in our Mulimedia Health Library.

Symptom Checker

Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.

Symptom Checker

Patient Privacy | Net Learning for Employees | MGMC PACS for Physicians
Emergency Preparedness

1111 Duff Avenue Ames, IA 50010 - 515-239-2011 - yourhealth.mgmc@mgmc.com

©2014 Mary Greeley Medical Center - All rights reserved.