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Multiple Sclerosis: Medicines for Fatigue

Topic Overview

Medicines used to treat fatigue caused by multiple sclerosis (MS) include:

  • Amantadine. This medicine typically has few side effects. When they do occur, they may include dry mouth, blurred vision, urinary retention, fluid retention, and rash.
  • Fluoxetine (Prozac). This antidepressant may help reduce fatigue in some people who have MS.
  • Modafinil (Provigil). This medicine is used to treat narcolepsy. It has also been used by doctors to treat fatigue in MS.

Related Information

Credits

By Healthwise Staff
Primary Medical Reviewer Adam Husney, MD - Family Medicine
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Barrie J. Hurwitz, MD - Neurology
Last Revised February 15, 2012

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