Home > Acquired Von Willebrand's Disease
Acquired von Willebrand's disease is a rare bleeding
disorder that tends to occur in older adults. It prevents blood from clotting
properly. It is rarer than the inherited form of
von Willebrand's disease.
believe acquired von Willebrand's disease may be caused by an autoimmune
disorder, in which the body's own
immune system attacks the blood system. Exactly what
triggers acquired von Willebrand's disease is not known. A genetic factor may
increase the risk of developing it.
Testing often reveals that
people who have acquired von Willebrand's disease also have one of the
Acquired von Willebrand's disease may also develop in direct
association with use of certain medicines. When use is discontinued, signs of
the disease also end. These medicines include:
nosebleeds with no previous history of bleeding
Treatment of acquired von Willebrand's disease includes medicines that help your body have enough von Willebrand clotting factor in
the blood. This von Willebrand factor helps your blood clot.
Other Works Consulted
Kessler CM (2008). Hereditary von Willebrand's disease
section of Hemorrhagic disorders: Coagulation factor deficiencies. In L
Goldman, D Ausiello, eds., Cecil Textbook of Medicine,
23rd ed., pp. 1308–1311. Philadelphia: Saunders Elsevier.
National Heart, Lung, and Blood Institute (2007).
The Diagnosis, Evaluation, and Management of von Willebrand Disease. (NIH Publication No. 08–5832). Available online:
November 22, 2010
E. Gregory Thompson, MD - Internal Medicine & Brian Leber, MDCM, FRCPC - Hematology
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